![]() Pyoderma gangrenosum (PG) is a condition in which skin sores form. Anal itching can be caused by many causes such as skin diseases, hemorrhoids, poor hygiene, too much washing, etc. Itchy anus: This is a severe and persistent itching in the area around the anus. Scalp psoriasis: is a common skin condition, red and white patches of skin with clear boundaries and very easy to peel and bleed accompanied by itching and hair loss, The difficulty of treating scalp psoriasis can make you quite uncomfortable even depressed if you are ridiculed or someone says something bad. ![]() Plaque psoriasis: This is a type of psoriasis characterized by red, dry patches of skin with white scales on top, may be accompanied by painful itching. Diagnosis of GA is clinical and can be done by biopsy. The disease is characterized by papules arranged in arcs or centrioles that surround normal or concave skin. Eczema: A type of allergy that causes red and itchy skin Contact Dermatitis: A type of skin rash caused by direct contact with an irritant Atopic Dermatitis Discoid Eczema Angioedema (GA): This is a chronic skin disease and benign. SD is diagnosed based on clinical examination, but the disease is difficult to distinguish from other diseases such as psoriasis, contact dermatitis, atopic dermatitis. with dry or greasy scaling of the scalp, more severe may have yellow-red papules. The disease usually develops gradually and often manifests itself. Seborrheic Dermatitis (SD): This is an inflammatory skin condition that mainly occurs in areas of the skin with many sebaceous glands such as the scalp, face, upper body, etc. In the early stages, the histopathology in biopsies may not be obvious. ![]() Diagnosis of the disease is based on clinical symptoms, laboratory results and skin biopsy results. The disease often has an indistinct onset, sometimes with only chronic redness at first. If a favorable response does not occur promptly, the corticosteroid should be discontinued until the infection has been adequately controlled.Triamcinolone Acetonide cream is used in the treatment of conditions such as: Skin T-cell lymphoma (CTCL): This is a rare disease, including mycosis (MF) and Sézary syndrome (SS), mainly Affects skin and lymph nodes. In the presence of dermatological infections, the use of an appropriate antifungal or antibacterial agent should be instituted. If irritation develops, topical corticosteroids should be discontinued and appropriate therapy instituted. Children may absorb proportionally larger amounts of topical corticosteroids and thus be more susceptible to systemic toxicity (see Infrequently, signs and symptoms of steroid withdrawal may occur, requiring supplemental systemic corticosteroids. Recovery of HPA axis function is generally prompt and complete upon discontinuation of the drug. If HPA axis suppression is noted, an attempt should be made to withdraw the drug, to reduce the frequency of application, or to substitute a less potent steroid. Therefore, patients receiving a large dose of a potent topical steroid applied to a large surface area or under an occlusive dressing should be evaluated periodically for evidence of HPA axis suppression by using the urinary free cortisol and ACTH stimulation tests. Systemic absorption of topical corticosteroids has produced reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, manifestations of Cushing’s syndrome, hyperglycemia, and glucosuria in some patients.Ĭonditions which augment systemic absorption include the application of the more potent steroids, use over large surface areas, prolonged use, and the addition of occlusive dressings. Some of the topical corticosteroids and their metabolites are also excreted into the bile. Corticosteroids are metabolized primarily in the liver and are then excreted by the kidneys. ![]() Corticosteroids are bound to plasma proteins in varying degrees. Once absorbed through the skin, topical corticosteroids are handled through pharmacokinetic pathways similar to systemically administered corticosteroids. Thus, occlusive dressings may be a valuable therapeutic adjunct for treatment of resistant dermatoses (seeĭOSAGE AND ADMINISTRATION). Occlusive dressings substantially increase the percutaneous absorption of topical corticosteroids. Inflammation and/or other disease processes in the skin increase percutaneous absorption. Topical corticosteroids can be absorbed from normal intact skin. The extent of percutaneous absorption of topical corticosteroids is determined by many factors including the vehicle, the integrity of the epidermal barrier, and the use of occlusive dressings.
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